Preheat the oven to 180°C (350°F).
In a large bowl, combine the ground beef, breadcrumbs, eggs, onion, garlic, milk, BBQ sauce, Worcestershire sauce, garlic powder, onion powder, smoked paprika, salt, and black pepper.
Fold in half of the cheddar cheese and half of the crumbled bacon.
Shape the mixture into a loaf and place it in a greased loaf pan or on a lined baking tray.
Mix the BBQ sauce and brown sugar, then spread the glaze over the meatloaf.
Bake for 50–55 minutes.
Sprinkle the remaining cheddar cheese and bacon over the top, then bake for another 10 minutes, until the cheese is melted and bubbly.
Let the meatloaf rest for 10 minutes before slicing and serving.
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